Base bibliographique

Sommaire :

Tumeur infiltrant le muscle chez le patient octogénaire : quelles solutions thérapeutiques proposées ?
2010
- Réf : Prog Urol, 2010, 4, 20, S57, suppl. S1


Le texte complet de cet article est disponible en PDF.
Cliquer ici pour le visualiser


Elderly are often the population affected by bladder cancer. Physician must consider not only a patient’s chronologic age but also physiologic age and associated medical conditions. Although radical cystectomy remains the treatment of choice for muscle invasive bladder cancer, it has a well-recognized risk of perioperative complications and mortality. Multidisciplinary oncogeriatric evaluation is necessary to detect associated comorbidities, and to improve oncologic decision and surgical outcomes. Radical cystectomy with ileal conduit is recommanded in elderly. Indications of conservative treatments depend on local extension, haematuria, and metastasis.

Mots clés:
Cancer de vessie / sujet âgé / Cystectomie radicale / Chimiotherapie / Bilan oncogériatrique
Mots-clés:
bladder cancer / Elderly / radical cystectomy / Hemotherapy / Oncogeriatric evaluation
Tumeur urothéliale de vessie chez le patient « fragile »
2010
- Réf : Prog Urol, 2010, 4, 20, S54, suppl. S1


Le texte complet de cet article est disponible en PDF.
Cliquer ici pour le visualiser


Adjuvant therapies in bladder cancer are based on risk of recurrence and associated comorbidities (renal failure). Lymph node involvement is the most important prognostic factor for decision. Two adjuvant chemotherapies exist: MVAC or GC. In unfit patients, association (Gemcitabine and Taxanes) could be proposed. Indication of adjuvant radiotherapy depends on metastatic risk and resection margins. Concomitant chemotherapy and radiotherapy should be proposed to selected patients who refuse or are not candidate for radical cystectomy.

Mots clés:
carcinome urothélial / Cancer de vessie / M-VAC / Cisplatine / Gemcitabine
Mots-clés:
Urothelial tumors / bladder cancer / M-VAC / Cisplatine / metastasis